A.1. Analysis of Stratumlevel when respondent sample size is 7,168
Total  7,168 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
1.47% 
1.57% 
1.95% 
2.09% 
2.24% 
2.39% 
2.39% 
2.56% 
2.44% 
2.61% 
1.47% 
2.61% 

30–44 
1.78% 
1.80% 
2.38% 
2.40% 
2.73% 
2.75% 
2.91% 
2.94% 
2.97% 
3.00% 
1.78% 
3.00% 

45–59 
2.51% 
2.35% 
3.35% 
3.13% 
3.84% 
3.59% 
4.10% 
3.83% 
4.19% 
3.91% 
2.35% 
4.19% 

60+ 
3.00% 
2.82% 
4.00% 
3.76% 
4.58% 
4.30% 
4.90% 
4.60% 
5.00% 
4.69% 

Min 
1.47% 
1.57% 
1.95% 
2.09% 
2.24% 
2.39% 
2.39% 
2.56% 
2.44% 
2.61% 
0.00% 
Overall Min 

Max 
2.51% 
2.35% 
3.35% 
3.13% 
3.84% 
3.59% 
4.10% 
3.83% 
4.19% 
3.91% 
4.19% 
Overall Max 

Summary statements for base sample size of 7,168 
With an overall base sample size of 7,168, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 4.19%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 47,787. If the active number rate is 20%, the number of MPNs that will need to be dialed is 238,935. 
A.2. Analysis of Stratumlevel when respondent sample size is 8,960
Total 
8,960 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
1.31% 
1.40% 
1.75% 
1.87% 
2.00% 
2.14% 
2.14% 
2.29% 
2.19% 
2.33% 
1.31% 
2.33% 

30–44 
1.60% 
1.61% 
2.13% 
2.14% 
2.44% 
2.46% 
2.61% 
2.63% 
2.66% 
2.68% 
1.60% 
2.68% 

45–59 
2.25% 
2.10% 
3.00% 
2.80% 
3.43% 
3.21% 
3.67% 
3.43% 
3.75% 
3.50% 
2.10% 
3.75% 

60+ 
2.68% 
2.52% 
3.58% 
3.36% 
4.10% 
3.85% 
4.38% 
4.11% 
4.47% 
4.20% 

Min 
1.31% 
1.40% 
1.75% 
1.87% 
2.00% 
2.14% 
2.14% 
2.29% 
2.19% 
2.33% 
0.00% 

Overall Min 
Max 
2.25% 
2.10% 
3.00% 
2.80% 
3.43% 
3.21% 
3.67% 
3.43% 
3.75% 
3.50% 

3.75% 
Overall Max 
Summary statements for base sample size of 8,960 
With an overall base sample size of 8,960, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 3.75%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 59,734. If the active number rate is 20%, the number of MPNs that will need to be dialed is 298,670. 
A.3. Analysis of Stratumlevel when respondent sample size is 12,544
Total 
12,544 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
1.11% 
1.18% 
1.48% 
1.58% 
1.69% 
1.81% 
1.81% 
1.93% 
1.85% 
1.97% 
1.11% 
1.97% 

30–44 
1.35% 
1.36% 
1.80% 
1.81% 
2.06% 
2.08% 
2.20% 
2.22% 
2.25% 
2.26% 
1.35% 
2.26% 

45–59 
1.90% 
1.77% 
2.53% 
2.37% 
2.90% 
2.71% 
3.10% 
2.90% 
3.17% 
2.96% 
1.77% 
3.17% 

60+ 
2.27% 
2.13% 
3.02% 
2.84% 
3.46% 
3.25% 
3.70% 
3.48% 
3.78% 
3.55% 

Min 
1.11% 
1.18% 
1.48% 
1.58% 
1.69% 
1.81% 
1.81% 
1.93% 
1.85% 
1.97% 
0.00% 

Overall Min 
Max 
1.90% 
1.77% 
2.53% 
2.37% 
2.90% 
2.71% 
3.10% 
2.90% 
3.17% 
2.96% 

3.17% 
Overall Max 
Summary statements for base sample size of 12,544 
With an overall base sample size of 12,544, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 3.17%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 83,627. If the active number rate is 20%, the number of MPNs that will need to be dialed is 418,135. 
A.4. Analysis of Stratumlevel when respondent sample size is 5,000
Total 
5,000 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
1.76% 
1.88% 
2.34% 
2.50% 
2.68% 
2.86% 
2.87% 
3.06% 
2.93% 
3.13% 
1.76% 
3.13% 

30–44 
2.14% 
2.15% 
2.85% 
2.87% 
3.26% 
3.29% 
3.49% 
3.51% 
3.56% 
3.59% 
2.14% 
3.59% 

45–59 
3.01% 
2.81% 
4.01% 
3.75% 
4.60% 
4.29% 
4.91% 
4.59% 
5.01% 
4.69% 
2.81% 
5.01% 

60+ 
3.59% 
3.37% 
4.79% 
4.50% 
5.49% 
5.15% 
5.87% 
5.51% 
5.99% 
5.62% 

Min 
1.76% 
1.88% 
2.34% 
2.50% 
2.68% 
2.86% 
2.87% 
3.06% 
2.93% 
3.13% 
0.00% 

Overall Min 
Max 
3.01% 
2.81% 
4.01% 
3.75% 
4.60% 
4.29% 
4.91% 
4.59% 
5.01% 
4.69% 

5.01% 
Overall Max 
Summary statements for base sample size of 5,000 
With an overall base sample size of 5,000, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 5.01%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 33,334. If the active number rate is 20%, the number of MPNs that will need to be dialed is 166,670. 
A.5. Analysis of Stratumlevel when respondent sample size is 7,000
Total 
7,000 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
1.48% 
1.59% 
1.98% 
2.11% 
2.27% 
2.42% 
2.42% 
2.59% 
2.47% 
2.64% 
1.48% 
2.64% 

30–44 
1.81% 
1.82% 
2.41% 
2.43% 
2.76% 
2.78% 
2.95% 
2.97% 
3.01% 
3.03% 
1.81% 
3.03% 

45–59 
2.54% 
2.38% 
3.39% 
3.17% 
3.88% 
3.63% 
4.15% 
3.88% 
4.24% 
3.96% 
2.38% 
4.24% 

60+ 
3.04% 
2.85% 
4.05% 
3.80% 
4.64% 
4.35% 
4.96% 
4.65% 
5.06% 
4.75% 

Min 
1.48% 
1.59% 
1.98% 
2.11% 
2.27% 
2.42% 
2.42% 
2.59% 
2.47% 
2.64% 
0.00% 

Overall Min 
Max 
2.54% 
2.38% 
3.39% 
3.17% 
3.88% 
3.63% 
4.15% 
3.88% 
4.24% 
3.96% 

4.24% 
Overall Max 
Summary statements for base sample size of 7,000 
With an overall base sample size of 7,000, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 4.24%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 46,667. If the active number rate is 20%, the number of MPNs that will need to be dialed is 233,335. 
A.6. Analysis of Stratumlevel when respondent sample size is 10,000
Total 
10,000 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
1.24% 
1.33% 
1.66% 
1.77% 
1.90% 
2.03% 
2.03% 
2.17% 
2.07% 
2.21% 
1.24% 
2.21% 

30–44 
1.51% 
1.52% 
2.01% 
2.03% 
2.31% 
2.32% 
2.47% 
2.49% 
2.52% 
2.54% 
1.51% 
2.54% 

45–59 
2.13% 
1.99% 
2.84% 
2.65% 
3.25% 
3.04% 
3.47% 
3.25% 
3.55% 
3.31% 
1.99% 
3.55% 

60+ 
2.54% 
2.38% 
3.39% 
3.18% 
3.88% 
3.64% 
4.15% 
3.89% 
4.23% 
3.97% 

Min 
1.24% 
1.33% 
1.66% 
1.77% 
1.90% 
2.03% 
2.03% 
2.17% 
2.07% 
2.21% 
0.00% 

Overall Min 
Max 
2.13% 
1.99% 
2.84% 
2.65% 
3.25% 
3.04% 
3.47% 
3.25% 
3.55% 
3.31% 

3.55% 
Overall Max 
Summary statements for base sample size of 10,000 
With an overall base sample size of 10,000, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 3.55%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 66,667. If the active number rate is 20%, the number of MPNs that will need to be dialed is 333,335. 
A.7. Analysis of Stratumlevel when respondent sample size is 15,000
Total 
15,000 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
1.01% 
1.08% 
1.35% 
1.44% 
1.55% 
1.65% 
1.66% 
1.77% 
1.69% 
1.80% 
1.01% 
1.80% 

30–44 
1.23% 
1.24% 
1.64% 
1.66% 
1.88% 
1.90% 
2.01% 
2.03% 
2.06% 
2.07% 
1.23% 
2.07% 

45–59 
1.74% 
1.62% 
2.32% 
2.16% 
2.65% 
2.48% 
2.84% 
2.65% 
2.89% 
2.71% 
1.62% 
2.89% 

60+ 
2.07% 
1.95% 
2.77% 
2.60% 
3.17% 
2.97% 
3.39% 
3.18% 
3.46% 
3.25% 

Min 
1.01% 
1.08% 
1.35% 
1.44% 
1.55% 
1.65% 
1.66% 
1.77% 
1.69% 
1.80% 
0.00% 

Overall Min 
Max 
1.74% 
1.62% 
2.32% 
2.16% 
2.65% 
2.48% 
2.84% 
2.65% 
2.89% 
2.71% 

2.89% 
Overall Max 
Summary statements for base sample size of 15,000 
With an overall base sample size of 15,000, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 2.89%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 100,000. If the active number rate is 20%, the number of MPNs that will need to be dialed is 500,000. 
A.8. Analysis of Stratumlevel when respondent sample size is 20,000
Total 
20,000 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
0.88% 
0.94% 
1.17% 
1.25% 
1.34% 
1.43% 
1.43% 
1.53% 
1.46% 
1.56% 
0.88% 
1.56% 

30–44 
1.07% 
1.08% 
1.42% 
1.43% 
1.63% 
1.64% 
1.74% 
1.76% 
1.78% 
1.79% 
1.07% 
1.79% 

45–59 
1.50% 
1.41% 
2.01% 
1.87% 
2.30% 
2.15% 
2.46% 
2.30% 
2.51% 
2.34% 
1.41% 
2.51% 

60+ 
1.80% 
1.69% 
2.40% 
2.25% 
2.74% 
2.58% 
2.93% 
2.75% 
2.99% 
2.81% 

Min 
0.88% 
0.94% 
1.17% 
1.25% 
1.34% 
1.43% 
1.43% 
1.53% 
1.46% 
1.56% 
0.00% 

Overall Min 
Max 
1.50% 
1.41% 
2.01% 
1.87% 
2.30% 
2.15% 
2.46% 
2.30% 
2.51% 
2.34% 

2.51% 
Overall Max 
Summary statements for base sample size of 20,000 
With an overall base sample size of 20,000, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 2.51%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 133,334. If the active number rate is 20%, the number of MPNs that will need to be dialed is 666,670. 
A.9. Analysis of Stratumlevel when respondent sample size is 25,000
Total 
25,000 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
0.79% 
0.84% 
1.05% 
1.12% 
1.20% 
1.28% 
1.28% 
1.37% 
1.31% 
1.40% 
0.79% 
1.40% 

30–44 
0.96% 
0.96% 
1.27% 
1.28% 
1.46% 
1.47% 
1.56% 
1.57% 
1.59% 
1.60% 
0.96% 
1.60% 

45–59 
1.35% 
1.26% 
1.79% 
1.68% 
2.06% 
1.92% 
2.20% 
2.05% 
2.24% 
2.10% 
1.26% 
2.24% 

60+ 
1.61% 
1.51% 
2.14% 
2.01% 
2.45% 
2.30% 
2.62% 
2.46% 
2.68% 
2.51% 

Min 
0.79% 
0.84% 
1.05% 
1.12% 
1.20% 
1.28% 
1.28% 
1.37% 
1.31% 
1.40% 
0.00% 

Overall Min 
Max 
1.35% 
1.26% 
1.79% 
1.68% 
2.06% 
1.92% 
2.20% 
2.05% 
2.24% 
2.10% 

2.24% 
Overall Max 
Summary statements for base sample size of 25,000 
With an overall base sample size of 25,000, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 2.24%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 166,667. If the active number rate is 20%, the number of MPNs that will need to be dialed is 833,335. 
A.10. Analysis of Stratumlevel when respondent sample size is 30,000
Total 
30,000 












Sex by Prevalence 

0.1 
0.2 
0.3 
0.4 
0.5 

Age 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Females 
Males 
Min 
Max 

18–29 
0.72% 
0.77% 
0.96% 
1.02% 
1.09% 
1.17% 
1.17% 
1.25% 
1.19% 
1.28% 
0.72% 
1.28% 

30–44 
0.87% 
0.88% 
1.16% 
1.17% 
1.33% 
1.34% 
1.42% 
1.43% 
1.45% 
1.46% 
0.87% 
1.46% 

45–59 
1.23% 
1.15% 
1.64% 
1.53% 
1.88% 
1.75% 
2.01% 
1.87% 
2.05% 
1.91% 
1.15% 
2.05% 

60+ 
1.47% 
1.38% 
1.96% 
1.84% 
2.24% 
2.10% 
2.40% 
2.25% 
2.44% 
2.29% 

Min 
0.72% 
0.77% 
0.96% 
1.02% 
1.09% 
1.17% 
1.17% 
1.25% 
1.19% 
1.28% 
0.00% 

Overall Min 
Max 
1.23% 
1.15% 
1.64% 
1.53% 
1.88% 
1.75% 
2.01% 
1.87% 
2.05% 
1.91% 

2.05% 
Overall Max 
Summary statements for base sample size of 30,000 
With an overall base sample size of 30,000, the maximum we will see estimating prevalences from 10% to 50% for each of four age and two sex categories is 2.05%. Assuming eligibility rates of 50% and response rates of 30%, the effective sample size is 200,000. If the active number rate is 20%, the number of MPNs that will need to be dialed is 1,000,000. 
A.11 Customizable Parameters for Sample Size Analysis
Parameter 
Code 
Active Number Rate 
ANR 
Eligibility Rate 
ER 
Response Rate 
RR 
Margin of Error 

Prevalence 
P 
Stratification Classes 
Strata 
Stratumlevel Misspecification Effect 
Meff_{S} 
Distribution of General Population across Strata 
Proportions 
Total Sample Size 
Total_n 